boltz-protein-design
Skill from boltz-bio/boltz-api-skills
Install
npx skills add boltz-bio/boltz-api-skills --skill boltz-protein-design
Runs the open skills CLI and installs the skill for your agent (Claude Code, Codex, Cursor …). Alternatively copy the skill folder into .claude/skills/ or upload it in Claude.ai under Settings → Skills.
As a Claude Code plugin
/plugin marketplace add anthropics/claude-plugins-official
/plugin install boltz@boltz-marketplace
This skill is part of the plugin “boltz”. In Claude Code the plugin installs it together with the plugin’s other skills, commands and hooks.
What does the boltz-protein-design skill do?
Description from the SKILL.md in the source repository.
Questions about boltz-protein-design
What does the boltz-protein-design skill do?
Design new protein binders with Boltz. Use when generating protein, peptide, antibody, nanobody, or custom binder candidates for a target. Not for screening existing proteins or small molecules.
How do I install boltz-protein-design?
In a terminal: npx skills add boltz-bio/boltz-api-skills --skill boltz-protein-design. The skills CLI asks which agents to install it for. In Claude.ai you can upload the skill folder as a ZIP under Settings → Skills.
Which agents can use boltz-protein-design?
Skills use the open SKILL.md format, which Claude Code, Claude.ai, the Claude API, OpenAI Codex, Cursor, Gemini CLI and other agents support.
Is boltz-protein-design safe to use?
Our automatic check found no risky patterns (piped shell scripts, hidden characters, secret access, prompt overrides). It is not a full audit – read the SKILL.md and any scripts before installing.
More skills from boltz-bio/boltz-api-skills
Boltz job status and result recovery. Use when listing jobs, checking progress, resuming downloads, recovering results, or downloading an existing job ID. Not for starting new jobs.
Screen existing protein binders with Boltz. Use when ranking a supplied protein, peptide, antibody, nanobody, or binder library against a target. Not for designing new proteins or screening small molecules.
Predict Tier-1 ADME/ADMET for small molecules with Boltz from bare SMILES — no target, no docking. Use when the user wants solubility, permeability, or lipophilicity/logD for a molecule or list of molecules. Not for ranking molecules against a protein target (use boltz-small-molecule-screen, which already returns ADME free).
Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking.
Screen existing small-molecule libraries with Boltz. Use when docking, scoring, or ranking a supplied SMILES or compound library against a target. Not for de novo molecule design or one-off docking.
Predict structures and binding for one defined complex with Boltz. Use when folding a protein, RNA, DNA, or ligand complex, docking one ligand, predicting an interface, or scoring binding. Not for screening libraries or design.
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